Paracetamol & Ibuprofen API – Key Antipyretic Analgesics for Global Healthcare
Paracetamol (Acetaminophen) and Ibuprofen are the most widely used antipyretic and analgesic API in the world.
They are essential for fever reduction, pain relief and common cold treatment in adults and children.
Sinophare provides high-purity Paracetamol API, Ibuprofen API and Aspirin API with GMP grade and stable batch quality.
We also offer finished dosage forms: Paracetamol tablets, Ibuprofen capsules and oral suspensions.
Bulk supply, customized packaging and fast delivery support global pharmaceutical production and distribution.
Product Description
| Classification | API >> Antipyretic analgesics >> Antipyretic and analgesic |
|---|---|
| Name | 4-Acetamidophenol |
| Synonyms | p-Hydroxyacetanilide; Acetaminophen; Paracetamol; N-Acetyl-4-aminophenol; APAP |
| Molecular Structure | ![]() |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 |
| CAS Registry Number | 103-90-2 |
| EC Number | 203-157-5 |
| SMILES | CC(=O)NC1=CC=C(C=C1)O |
Related
Specification
Strength: Paracetamol 1000mg (1g)
Volume: 100mL
Description
Paracetamol is a centrally acting analgesic and antipyretic. It inhibits prostaglandin synthesis in the central nervous system, relieves moderate pain and reduces fever, with negligible anti-inflammatory effect. Intravenous infusion ensures rapid onset and stable efficacy, well-tolerated for clinical critical and perioperative use.
Indications
Moderate to severe acute pain, including postoperative pain
Persistent fever unresponsive to other treatments
Fever and pain management for patients unable to take oral medicine
Adjuvant symptomatic treatment for infectious fever
Storage
Store tightly sealed at room temperature, protected from light.
Do not freeze.
Use promptly once opened.
Keep out of reach of children.
Warning
For intravenous infusion only.
Contraindicated in paracetamol hypersensitivity, severe hepatic impairment.
Strictly control daily dosage to prevent hepatotoxicity.
Do not combine with other paracetamol-containing preparations.
Use with caution in renal insufficiency, chronic alcoholism and malnourished patients.
Specification
Concentration: Paracetamol 160 mg / 5 mL
Pack size: 60 mL
Description
Paracetamol is a centrally acting antipyretic and analgesic agent. It inhibits central prostaglandin synthesis to relieve pain and reduce fever, with weak anti‑inflammatory effect and good gastrointestinal tolerance. Oral suspension is easy to administer, ideal for pediatric patients.
Indications
Fever caused by cold, flu and various inflammatory conditions
Relief of mild to moderate pain: headache, toothache, sore throat, myalgia
Pain and fever relief for children unable to take solid tablets
Storage
Store at room temperature, tightly sealed, protect from light.
Shake well before use.
Keep out of reach of children.
Warning
For oral use only.
Contraindicated in patients with hypersensitivity to paracetamol.
Do not use together with other paracetamol‑containing preparations.
Avoid overdose to prevent irreversible hepatic injury.
Use with caution in patients with liver and renal impairment.
Each vial contains:
Acetylcysteine …… 1.0 g
Description
Acetylcysteine Injection is a sulfhydryl-containing compound. It breaks disulfide bonds in mucus glycoproteins to thin viscous sputum, and also acts as an antidote by restoring glutathione levels to protect the liver in acetaminophen overdose.
Indications
Respiratory diseases with thick, sticky sputum: bronchitis, pneumonia, COPD, tracheostomy care
Paracetamol (acetaminophen) poisoning and liver injury prevention
Adjuvant treatment for atelectasis due to mucus obstruction
Storage
Store in a cool, dry place, protected from light.
Reconstituted solution should be used promptly.
Keep out of reach of children.
Warning
Prescription drug for intravenous infusion / instillation use only.
Contraindicated in patients with hypersensitivity to acetylcysteine.
Use with caution in asthma, peptic ulcer, and hepatic or renal impairment.
May cause nausea, rash, bronchospasm, or hypotension.
Use under medical supervision.
Each vial/ampoule contains:
Paracetamol (Acetaminophen) …… 500 mg
Description
Paracetamol (Acetaminophen) Injection is a centrally acting analgesic and antipyretic agent. It inhibits prostaglandin synthesis in the central nervous system to relieve pain and reduce fever, with mild anti-inflammatory effect.
Indications
Short-term treatment of moderate to severe acute pain
Postoperative analgesia
Fever control when oral administration is not feasible
Adjunctive antipyretic for infectious fever
Storage
Store in a cool, dry place, protected from light.
Do not freeze.
Keep out of reach of children.
Warning
For intravenous infusion / slow intravenous injection only.
Contraindicated in patients with hypersensitivity to paracetamol, severe hepatic insufficiency or active liver disease.
Avoid high doses or prolonged use to prevent hepatotoxicity.
Do not use concurrently with other paracetamol-containing products.
Use with caution in renal impairment, malnutrition, dehydration or alcohol abusers.
Paracetamol (Acetaminophen) Tablets 500mg are a widely used antipyretic and analgesic.
It works by inhibiting prostaglandin synthesis in the central nervous system, providing safe and effective fever reduction and pain relief with good gastrointestinal tolerance.
Composition
Each tablet contains:
Paracetamol (Acetaminophen) …… 500 mg
Indications
Fever caused by common cold, influenza and other infections
Mild to moderate pain: headache, migraine, toothache, muscle pain, joint pain, dysmenorrhea, sore throat
Key Features
Reliable antipyretic and analgesic effect
Good safety profile at recommended dosage
Well tolerated by most people
Oral administration, convenient to take
Complies with CP / USP / EP pharmacopoeial standards
Manufactured under strict GMP conditions
Complete registration dossiers available for global markets
Storage
Store in a cool, dry place, sealed and protected from light.
Keep out of reach of children.
Note
Do not use with other paracetamol-containing products to avoid overdose.
Use with caution in patients with impaired liver function.
Paracetamol Effervescent Tablets 500 MG are an oral antipyretic and analgesic. The effervescent formulation dissolves rapidly in water, creating a pleasant, effervescent solution that is easy to ingest and rapidly absorbed by the body.
It acts by inhibiting prostaglandin synthesis in the central nervous system, effectively reducing fever and relieving mild to moderate pain.
Composition
Each effervescent tablet contains:
Paracetamol (Acetaminophen) …… 500 mg
Indications
For the relief of:
Fever: Associated with the common cold, influenza, and other acute respiratory infections.
Pain: Headache, toothache, muscle pain, menstrual pain, neuralgia, and mild to moderate postoperative pain.
Key Features
Rapid onset: Effervescent dissolution ensures quick uptake, with pain relief typically occurring within 30-60 minutes.
Refreshing taste: The effervescent formula is palatable and easy to take, especially for those who have difficulty swallowing tablets.
High patient compliance: Convenient oral administration and well-tolerated when used as directed.
Stable quality: Manufactured under strict GMP conditions, compliant with pharmacopoeial standards (USP, EP, BP).
Complete registration dossiers available for global market access and export.
Storage
Store in a cool, dry place, sealed and protected from light and moisture.
Keep out of reach of children.
Important Note
Contraindications: Hypersensitivity to paracetamol or any ingredient in the formulation.
Warnings: This medication contains paracetamol. Do not take with other medicines that also contain paracetamol to avoid accidental overdose.
Cautions: Use with caution in patients with liver disease or chronic alcohol consumption.
Interaction: May interact with anticoagulants (e.g., warfarin); consult a doctor if taking other medications.
Composition per tablet
Paracetamol 500 mg
Diphenhydramine Hydrochloride 25 mg
Chlorphenamine Maleate 2 mg
Product Description
Compound Paracetamol Tablets are a multi‑action cold preparation combining paracetamol with two antihistamines. It provides effective fever reduction, pain relief, and alleviation of nasal and allergic symptoms caused by the common cold, influenza, or upper respiratory tract infections.
Indications
For the relief of fever, headache, sore throat, body aches, runny nose, sneezing, nasal congestion, and other cold‑related symptoms.
Key Features
Combined antipyretic, analgesic and antihistamine action
Relieves multiple cold symptoms in one tablet
Oral administration, convenient for daily use
Stable composition and reliable efficacy
Strict quality control in line with pharmacopoeial standards
Manufactured under GMP conditions
Complete registration dossiers available for global markets
Storage
Store in a cool, dry place, sealed and protected from light and moisture.
Keep out of reach of children.
Paracetamol Suppository is a rectal analgesic and antipyretic pharmaceutical product that delivers paracetamol directly through the rectal mucosa.
It is widely used for the relief of fever caused by colds, infections, vaccinations, as well as mild to moderate pain including headache, toothache, postoperative pain and musculoskeletal pain. Suppository form is especially suitable for infants, young children, vomiting patients, and those unable to take oral medications.
Key Features:
Rapid absorption and fast onset of effect
Avoids gastrointestinal irritation and first-pass metabolism
Easy to administer, non-invasive
Suitable for children and adults with various specifications
Stable, safe and well-tolerated
Manufactured under strict GMP standards
Complete registration dossiers available for export
Storage
Store in a cool, dry place, avoid high temperature and direct sunlight.
Specification
Concentration: Ibuprofen 100mg per 5mL
Pack size: 60mL per bottle
Description
Ibuprofen belongs to non-steroidal anti-inflammatory drugs. It inhibits prostaglandin synthesis to achieve reliable analgesic, antipyretic and anti-inflammatory effects. The oral suspension formula is easy to take, rapidly absorbed, mild and suitable for pediatric administration.
Indications
Reduce fever induced by common cold, influenza and inflammation
Relieve mild and moderate pain: headache, sore throat, toothache, myalgia
Alleviate inflammatory discomfort of soft tissue and joint swelling pain
Storage
Store tightly closed at room temperature, protect from light.
Shake well before each use.
Keep out of reach of children.
Warning
For oral use only.
Contraindicated in patients with ibuprofen hypersensitivity, active peptic ulcer and severe organ dysfunction.
Use with caution in asthma, gastrointestinal disease and renal impairment patients.
Do not combine with other NSAIDs or exceed the recommended dose.
Short-term use only; discontinue and seek medical advice if discomfort occurs.
Ibuprofen Tablets 100 mg are a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis, offering analgesic, antipyretic and anti-inflammatory effects.
The 100 mg strength is especially suitable for children and mild symptom relief.
Composition
Each tablet contains:
Ibuprofen …… 100 mg
Indications
Relief of mild to moderate pain: headache, toothache, neuralgia, muscle pain, menstrual pain
Reduction of fever caused by colds, influenza and other infections
Relief of inflammatory symptoms: arthritis, soft tissue injury inflammation
Key Features
Rapid onset, reliable effect
100 mg low dose, suitable for pediatric use
Good safety and tolerance
Oral administration, easy to take
Stable quality compliant with pharmacopoeial standards
Produced under GMP conditions
Complete registration dossiers available for global markets
Storage
Store in a cool, dry place, sealed and protected from light and moisture.
Keep out of reach of children.
Ibuprofen Suppository is a rectal non-steroidal anti-inflammatory drug (NSAID) with effective antipyretic, analgesic and anti-inflammatory effects.
It is widely used for the relief of fever caused by colds, infections, vaccination reactions, and for the treatment of mild to moderate pain such as toothache, headache, earache, sore throat, musculoskeletal pain and postoperative pain. The suppository form is especially suitable for infants, young children, vomiting patients and those with difficulty swallowing.
Key Features:
Rapid fever reduction and long-lasting effect
Rectal absorption, avoids gastrointestinal irritation
Easy to administer, non-invasive
Suitable for both pediatric and adult use
Safe and well-tolerated at recommended doses
Manufactured under strict GMP standards
Complete registration documents available for export
Storage
Store in a cool, dry place, protected from light and high temperature. Do not freeze.

