Intravenous infusion only (after reconstitution and dilution). NOT for intramuscular, subcutaneous, or direct intravenous bolus injection. Infuse over approximately 10 minutes.
Packaging
100mg sterile type I glass vial with rubber stopper and aluminum flip-off seal
Storage
Store below 25°C, protected from light. Do not freeze. Keep vial in outer carton until use. Reconstituted and diluted solutions should be used within 24 hours if refrigerated (2–8°C), or within 12 hours at room temperature (below 25°C).
Shelf Life
36 months (unopened)
Product Overview
Pemetrexed Disodium for Injection 100mg is a sterile, nonpyrogenic, lyophilized powder intended for reconstitution with 0.9% Sodium Chloride Injection (preservative-free) and further dilution prior to intravenous infusion. Each vial contains pemetrexed disodium equivalent to 100mg of pemetrexed free acid. Pemetrexed is a multitargeted antifolate antimetabolite with activity against rapidly dividing cells. The intravenous formulation is designed for use in adult patients with malignant pleural mesothelioma (in combination with cisplatin) and locally advanced or metastatic non-small cell lung cancer (NSCLC) (as second-line therapy or maintenance therapy following platinum-based chemotherapy).
